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Recent efforts to improve in vitro liver models have underscored the importance of three-dimensional (3D) hepatocyte cultures, which better recapitulate in vivo architecture and function than traditional two-dimensional systems and are increasingly applied for drug metabolism, disposition, and toxicity studies

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The patent for semaglutide expired in India and China in late-March, which led to a flurry of generic GLP-1s launched by all major Indian pharmaceutical companies, starting from as little as 2,500/month