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Description
Following the removal of duplicates and excluding studies based on the eligibility criteria, a total of 5 case series and 22 case reports remained, which were considered for this systematic review [7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31]
In addition, in vitro studies have shown that recombinant TTR amyloid aggregates are internalized by human cardiac fibroblasts, which subsequently secrete IL-6 and IL-8, providing mechanistic evidence that TTR aggregates can trigger inflammatory responses in cardiac cells [77]

Side Effects: Most people experience none or mild effects such as redness or tenderness at the injection site

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Youre wearing your double-layered mask, armed to the teeth with wet wipes, and should anyone dare get closer than two metres, so help you, theyre getting sprayed with extra-strength sanitiser

Release 194 , 323331 (2014)
