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In addition, we hypothesize that the unique bioenergetic compensatory mechanisms that we observe in the EC may lead to an increased rate of reactive oxygen species (ROS) generation in this region, which may play a causative role in the pathogenesis of AD among APOE4 carriers
Ross, D.A
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However, in another study, acetyl-l-carnitine therapy (50 mg/kg, i.p., 6 weeks) positively impacted the regeneration of unmyelinated fibres in the sciatic nerve based on a stereological analysis of myelinated/unmyelinated axon numbers, surface area, myelin thickness, and the myelin thickness-to-axon diameter ratio [45]
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