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doi: 10.1093/eurheartj/ehr304
Mechanistically, these agents activate the Nrf2/ARE, NF-B, MAPK, PI3K/Akt/mTOR, and SIRT1/PGC-1 pathways, protect mitochondria and the bloodnerve barrier, and upregulate endogenous antioxidant enzymes
We also showed that cells lacking Munc13-4 expression have an accumulation of enlarged endosomes
S., Koh H
doi:10.1056/NEJM200009213431204 36
Eggers regression test corroborated this finding, yielding a non-significant intercept (0.20
