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Funding This work was supported by the: Parkinson Research Consortium of Ottawa (J.M.T., D.N.E.K., T.K.F., J.J.T., A.C.)

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in this study, measures only the total Trx1 pool that includes Trx1-reduced and Trx1-oxidized, but do not enable identification of Trx1 redox state

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Supporting this sequence of events is the finding that ROS production by commensal bacteria-inactivated dual-specific phosphatase 3 leads to ERK activation (92)
