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Contribution of classification based on ferroptosis-related genes to the heterogeneity of Mafld

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Principal component analysis (PCA) showed that HCV29RP and m705RP cells had a distinct transcriptomic profile compared with parental cells or parental cells treated with short-term (24 hours) rapamycin or the bi-steric RMC-6272 (Figure 3A and Supplemental Figure 3A)

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Interestingly, Nrf2 expression is significantly downregulated in peritoneal tissue-resident macrophages isolated from Immune-responsive gene 1 ( Irg1 ) shRNA-injected tumor-bearing mouse (79)