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Description
Our previous study revealed that GSTM1 was required for the optimal activation of NF-B, a critical transcription factor for the expression of pro-inflammatory genes downstream of TNF- signaling ( via S -glutathionylation ( GSTM1 in astrocytes may also be involved in aging-associated changes in the brain and possibly aging-associated neurodegenerative diseases

The effect of SF on the gut microbiome may also affect the production of short-chain fatty acids (SCFA) like butyrate, which have neuroprotective effects [149,150]

Drawing on evidence from literature that demonstrates the reduced levels of GSH in the main conditions clinically associated with severe disease, we highlight the relevance of restoring GSH levels in the attempt to protect the most vulnerable subjects from severe symptoms of COVID-19
Eskow Jaunarajs, K

doi:10.1016/j.smim.2017.12.005 Narasimhan, Prakash Babu et al

J Ophthalmol 2015;2015:1-10
