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Although the pathological hallmark of PD is the accumulation of alpha-synuclein-containing Lewy bodies, most patients also have varying degrees of other pathological accumulations, including beta-amyloid plaques and tau-tangles, which are more strongly linked with dementia onset and poor outcomes 2

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Bradshaw P.C

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This upregulation correlated with reductions in adipose tissue mass

(2003) Deng, A., Himmelsbach, M., Zhu, Q.-Z., Frey, S., Sengl, M., Buchberger, W., Niessner, R., and Knopp, D
Veldhuis, J