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Unlike GLP-1 agonists that reduce appetite or growth hormone peptides that stimulate lipolysis, the compound addresses fat metabolism at the enzymatic level: it removes the molecular governor that locks adipocytes into a low-energy-expenditure state, potentially restoring normal metabolic function in fat tissue where NNMT is overexpressed

They'll be much bigger and shaped differently than healthy ones

It works by acting directly on fat cells, stimulating lipolysis (the breakdown of stored fat) and inhibiting lipogenesis (the formation of new fat)

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Inflammation and perivascular infiltrate: 0 = 01 intralobular or perivascular leukocytes/HPF

doi: 10.1001/jamanetworkopen.2020.34074 109 KimD-YParkEHeoCYJinUSKimEKHanWet al