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The stabilized NRF2 then translocates into the nucleus, attaches to antioxidant response elements (AREs) in gene promoters, and regulates the transcription of target genes involved in antioxidant responses and cellular redox maintenance

Researchers continue to study the antioxidant, publishing promising results annually

An important process is nitric oxide inactivation through its reaction with superoxide radicals, which results in the formation of peroxynitrite ONOO

Another great testament to glutathiones efficacy is shown in the reduction of malondialdehyde, a marker of hepatic cell damage

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The size of the studies, the consistent methodology, and the studies designs (described as robust) provide solid evidence and a strong argument that paracetamol use during pregnancy leads to an increased risk of neurodevelopmental disorder diagnosis in children