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This residual risk is likely attributable at least in part to inflammation

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SREBP2 must be translocated from the ER to the Golgi apparatus, where it is released from the membrane by site 1 protease (S1P) and site 2 protease (S2P) 15
Combination therapy with ibrexafungerp (Formerly SCY-078), a first-in-class triterpenoid inhibitor of (13)--d-glucan synthesis, and isavuconazole for treatment of experimental invasive pulmonary aspergillosis

11 Hegaze AH, Hamdi AS, Alqrache A, Hegazy M