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The oxidative branch of the pentose phosphate pathway (PPP), driven primarily by the enzymes glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD), continues to serve as the dominant metabolic source of NADPH in most cells [42]

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It also helps shift the balance from darker eumelanin to lighter pheomelanin, which can result in a brighter and more even skin tone

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