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Several studies have shown that obesity is an independent risk factor for the onset of CKD as well as its severity

However, the presence of the corresponding functional genes does not mean that these genes are expressed to contribute to the specific biodegradation/biofiltration process

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Livraghi-Butrico et al., 2013

1 - 13 This point was illustrated by the evidence obtained in rats in which abdominal aorta anastomosis (and thereby arterial thrombosis), 94 or inferior caval vein occlusion (and thereby venous thrombosis), 101 or amputation and anticoagulants application (and thereby prolonged bleeding and thrombocytopenias) 63 , 64 were present

ER, estrogen receptor