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Applying genome-wide CRISPR-Cas9 screens for therapeutic discovery in facioscapulohumeral muscular dystrophy

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10.1371/journal.pgen.1001070 73 UenoK.OkawaraA.YamagoeS.NakaT.UmeyamaT.Utena-AbeY.et al

Tena-Campos M, Ramon E, Borroto-Escuela DO, Fuxe K, Garriga P

It has been reported that resveratrol causes the reversal of promotor hypermethylation and the restoration of tumor suppressor genes

C57BL/6J male mice at 8- to 10-week-old age were intraperitoneally injected with saline or kainic acid (KA), an analog of glutamate
