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93,94 In humans, vitamin C has been shown in multiple randomized, double-blind, placebo-controlled trials to help with both depression and anxiety in patients of various ages as well as with opioid addiction

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Selecting a suitable SELEX protocol requires careful consideration of factors such as RNA handling capabilities, equipment availability, desired dissociation constant (K d ), target nature, time and cost efficiency, and potential post-SELEX modifications (Mascini and Mascini, 2009)