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Brain and plasma levels of tryptophan also increased significantly following oral repeated administration of NSO

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Problems due to lack of cell division in fast dividing tissues: Anaemia, or any cytopaenia (including leucocytes, lymphocytes, platelets) Mouth ulcers, malabsorption, diarrhoea due to macrocytosis and atrophy of the intestinal mucosa as demonstrated by Foroozan and Trier