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Additional studies are required to understand the molecular and physiological effects of glucocorticoid signaling via GR or MR in the heart

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J Biol Chem 256:1238712392 Larraufie M-H, Yang WS, Jiang E et al (2015) Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility

However, the toxicity of nanomaterials is not an insurmountable challenge

the main clinical issues are liver disease, arthritis and dementia

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