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Less common causes include coagulopathy, vasculitis, and endocarditis

Biochim et Biophys Acta (BBA) Mol Cell Biol Lipids 1791(7):671678 Vanier MT, Millat G (2004) Structure and function of the NPC2 protein

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207,208 Several analogs have been designed and shown to have potent antibacterial activity, but thus far none have made it to the clinic, hindered in large part by adverse pharmacodynamics related to the necessity of a lipid tail to achieve the full antibacterial activity

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