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CJC-1295 + Ipamorelin is a USA-manufactured dual-peptide GH axis research blend combining CJC-1295 No DAC (ModGRF 1-29) a synthetic GHRH analogue that activates the GHRH receptor on anterior pituitary somatotrophs via Gs-cAMP signaling and Ipamorelin, a selective GH secretagogue that activates the ghrelin receptor (GHS-R1a) via the distinct Gq/11 intracellular pathway, providing simultaneous dual-receptor GH axis stimulation in a single research preparation

Sublingual liquid for fast absorption

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The blend supplied here is for laboratory and research use only and is not approved for diagnostic, therapeutic, or human use

DOI: 10.1111/j.1365-2826.2008.01733.x 20

As for patients with GHD and concurrent diseases with intra-portal hypoinsulinemia (e.g., T1D and inflammatory diseases), higher GH doses are required to normalize IGF-I levels, which has cost implications