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114 Prolonged exposure to alcohol leads to the release of oxidized mitochondrial DNA via extracellular vesicles in ALDH2-deficient mouse liver cells, and this DNA is transferred to nearby HCC cells and activates carcinogenic (JNK, STAT3, BCL2, and transcriptional coactivator with PDZ-binding motif) pathways, promoting the development of alcohol-related HCC
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Long-Term Sildenafil Added to Intravenous Epoprostenol in Patients with Pulmonary Arterial Hypertension
