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Sensitivity analysis excluding this sample did not materially alter group separation, suggesting biological heterogeneity rather than analytical artifact

The gap between doing it right and doing it wrong comes down to timing, dosage alignment, and understanding what each component actually does

Defective mitochondrial function and impaired energy metabolism are highly implicated in the pathogenesis of PD [8]

Methylsulfonylmethane (MSM): Can convert into hydrogen sulfide (H2S) with certain bacterial overgrowths in the gut

This deficiency restricts tissue uptake, leading to decreased accumulation in the heart and skeletal muscle and potentiates increased renal carnitine loss [21, 22] leading to systemic carnitine depletion [23]