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For example, IL-1 promotes BMSC migration via the NF-B pathway but inhibits their chondrogenic differentiationan effect that can be alleviated under hypoxic conditions (Teixeira et al., 2018)

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286 - 289, Journal articles | 1999 Jaff A

These characteristics make it beneficial for managing conditions related to chronic pain and inflammation

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Several studies demonstrated that MSM inhibits lipopolysaccharide-induced release of oxidative stress biomarkers, such as nitric oxide and prostaglandin E2 in macrophages, through downregulation of NF- B signaling [145, 146]
