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Touyz RM, Schiffrin EL

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Oral administration of pregabalin (at a target dose of 150 mg/day in three divided doses, much less than gabapentin) significantly reduced the severity of sensory neuropathy induced by oxaliplatin by 1-2 grades

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Immunity 36 , 10731086 (2012)

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10.1056/NEJM199403033300907 58 LiuH.DengY.GaoJ.LiuY.LiW.ShiJ.et al

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Icariin and icaritin exert anti-cancer effects through regulating gut microbiota Although its entire potential in cancer treatment has not yet been investigated, it has been discovered that icariin regulates the human intestinal microbiota

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Subsequent deprotonation and dehydrohalogenation lead to the formation of 2-hydroxyindole and/or its tautomer, 3-substituted-2-oxindole [11,14]

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