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Hypertension 72, 350360

Mol Cell (2019) 75:64460.e645

The adaptive significance of shrinkage is debated but plausible mechanisms include selection for replication economy in high-density aquaculture (where faster replication or reduced genomic maintenance costs could confer competitive advantages), genetic drift and repeated founder events during anthropogenic translocations, and molecular mechanisms such as recombination at repeat motifs that produce deletion variants

The relative cell viability, expressed as a percentage of DMSO- or compound-treated cells under erastin treatment, is summarized as a heatmap (Fig

Bare AuNPs tend to exhibit lower stability, are prone to aggregation, and can generate interfering background ions in the form of metal cluster species

On the other hand, targeted drugs may require less time and cost in the initial stage of development but could necessitate more late-stage investment to address resistance and side effects