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L-arginine-dependent formation of N-nitrosamines by the cytosol of macrophages activated with lipopolysaccharide and interferon-gamma

GI changes (constipation or diarrhea) are more often linked to B12 deficiency or underlying gut conditions that also impair B12 absorption

10.1093/toxsci/kfn243 2 AdlerV.YinZ.FuchsS

doi: 10.1007/BF01071903 [DOI] [PubMed] [Google Scholar] 25.da Silva A, Caldas APS, DMUP R, Bressan J

Adding less than 0.5 mL to any vial makes accurate dosing extremely difficult with standard syringes

Interestingly, drinking caffeinated coffee was correlated with lower risk of rosacea in one observational study that included 82,737 female subjects
