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Vitamin B12 can be converted to coenzyme B12 in tissues, and as such is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine, a reaction which also requires folate

In contrast, oxidase-like nanozymes require simpler reaction conditions (avoiding the addition of H 2 O 2 )

( Butyrate also provides direct anti-inflammatory benefits by inhibiting key pro-inflammatory signaling pathways, thereby counteracting cytokine-driven disruption of tight junction integrity

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Verkaik-Kloosterman, J., vant Veer, P