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Introduction Major depressive disorder (MDD) is one of the most common psychiatric disorders and is characterized by marked mood swings with sadness or irritability and psychophysiological changes such as sleep, appetite, and libido disturbances lasting for at least 2 weeks ( Metabolomics is the study of small molecules (up to 1.5 kDa) called metabolites

Furthermore, when low energy stems from a chronic condition, like depression or Graves disease, treating the underlying condition often helps boost energy levels

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Thirty mg (30 mg) of Span 60, cholesterol (molar ratio: 1:1), and 10 mg of LC were dissolved in a solution of methanol and chloroform in a round flask