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A key hypothesis we are studying here is that in endometriosis, a pro-oxidant microenvironment in the local vicinity of the follicle created by an unbalanced redox state detrimentally impacts the quality of oocytes, sperm, and embryos, hampering their cellular function, jeopardizing their viability, and that this is a fundamental underlying cause of diminished fertility with endometriosis

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The power of fluorescence spectroscopy in application to proteins is reflected in the ability of this technique to provide characterization of protein flexibility across a wide range of timescales, from picoseconds to seconds and even minutes, with the specific timescale observed being dependent on the type of motion being measured and the fluorescence method used

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