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NSI-189 is a novel benzylpiperazine-aminopyridine compound, which has been investigated for the treatment of major depressive disorder (MDD) amongst other cognitive deficits

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Blackwell TK, Steinbaugh MJ, Hourihan JM, Ewald CY, Isik M (2015) SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans

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This chelation allows the complex to act as a biologically active copper carrier, capable of delivering copper to cellular proteins and enzymes that depend on trace metal cofactors for activity

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