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This is believed to be due to their relatively short generation time at chill temperatures (Morita, 1975

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Although a variant transketolase enzyme has been proposed to be associated with Wernicke-Korsakoff syndrome, no mutations have been found in the gene (symbol: TKT) encoding this enzyme when cloned from patients exhibiting the syndrome

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In vitro experiments showed a phosphorylation reaction of AMPK after initial intervention with AMPK inhibitors in BV2 cells