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injections of doses of 20, 100, or 500 g/kg to rats, the peak time (Tmax) of each dose was 3 min, while the Cmax of each dose was equivalent to 12.3, 48.9, and 141 ng/mL, respectively

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[8] The total world production of vitamin B 12 , by four companies (the French Sanofi-Aventis and three Chinese companies) in 2008 was 35 tonnes