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The best thing about this therapy is that, unlike oral supplements, it bypasses absorption barriers

doi: 10.1038/s41392-020-00315-3 141 LublinF

Matched-pair analysis following log transformation was used to compare the conditions

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On top of its important role as the powerhouse of the cell, these organelles are also essential regulators of cellular metabolism, redox state, intracellular calcium signaling, and programmed cell death mechanisms [12,13,14,15]

That is very dangerous, and may lead to permanent nerve damage
