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Copper-based MOFs can be particularly effective for redox-enabled therapies, yet uncontrolled Cu ion release and ROS stress may raise off-target toxicity concerns, underscoring the need for careful exposure control and safety testing ( On the other hand, the main bottleneck for nucleic acid therapies is the duration of effective exposure, rather than a transient peak

In patients with psoriasis, alcohol exposure led to increased lymphocyte activity, a response not observed in healthy individuals

Cooke NCA, Bala A, Allard JP, Hota S, Poutanen S, Taylor VH