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Encapsulation of DDA-GSH-AuNCs into PLGA nanoparticles using the emulsion-evaporation method PLGA (30 mg) was dissolved in chloroform containing DDA-GSH-AuNCs (1.5 mL), and then emulsified into aqueous PVA solution (2.5% w/w, 5.0 mL) using sonication for 60 s (ultra-probe sonicator at 50 W, UP200Ht, Hielscher Ultrasonics, Teltow, Germany)

doi: 10.25135/jcm.17.18.05.094

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5.3 The challenge of clinical translation 5.3.1 Lack of large-scale randomized controlled trials (RCTs) The potential of functional food active ingredients in combating conditions such as cancer has received widespread attention at the in vitro and animal levels, but high-quality human evidence is relatively scarce