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(2016) Simultaneous determination of the main amino thiol and thione in human whole blood by CE and LC

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In addition to ALP, other CD-based sensors have been reported for the detection of protein and enzyme biomarkers such as hyaluronidase, acetylcholinesterase, and uric acid [219,220,221]

The histidine residue serves as the primary copper-binding site, while the lysine residue contributes to cellular uptake through electrostatic interactions with negatively charged cell membranes

Upon binding to cytoplasmic glucocorticoid receptors (GR), corticosteroids induce translocation of GR complexes into the nucleus, where they interact with glucocorticoid response elements (GREs) to upregulate anti-inflammatory genes (e.g., IL-10, DUSP-1) and suppress pro-inflammatory mediators like IL-1, IL-6, TNF-, and chemokines, such as MCP-1 and IL-8 (McManus 2003

The objective of the in vivo study was to evaluate glutathione GSH absorption in 15 healthy volunteers