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Except for CNAG_01500, all other genes in this cluster are up regulated in the gpp2 strain

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A retinoic acid deficiency could also occur, even in the absence of heritable alcoholism, if errors in a gene pair involved in retinol metabolism produce an accumulation of retinal and a lower amount of retinoic acid

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The study demonstrated elevated pain thresholds following DSIP administration in the hot plate test, particularly during the dark phase, and the effect was not blocked by naloxone, indicating a non-opioid analgesic mechanism

BW higher than 22.5 kg/m 2 has been observed to increase CVD and T2D risk substantially, contributing to more than 30% of global human mortality