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Using cultured human fibroblasts under oxidative stress conditions: Ergothioneine treatment resulted in significantly longer median telomere length after 8 weeks The percentage of short telomeres was significantly reduced across all tested concentrations The rate of telomere shortening was decreased Effects were dose-dependent at physiologically relevant concentrations Dr

EGCG-based nanoparticles: synthesis, properties, and applications

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In particular, BHB, in addition to its role as an energy source, also has a variety of molecular signaling and regulatory functions in a wide range of human diseases ( 4.1 Epigenetic regulation BHB has been reported as a Class I histone deacetylase (HDAC) inhibitor and an endogenous neuroprotective epigenetic modifier ( 4.2 Gut microbiome Gut microbes are also known to be involved in the development of many diseases

Lower AHR expression has been described as a potential mechanism of pathogenesis for several autoimmune conditions including inflammatory bowel disease (125), multiple sclerosis (126), and psoriasis (127)