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Therefore, to address whether p53 is involved in controlling the cellular tolerance to FA, we inactivated the gene coding for this factor ( TP53 ) and the one coding for ADH5 in HCT116 cells (Supplementary Fig
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Experimental studies have indicated that saffron aqueous extract may improve memory deficits in diabetic rats by affecting GSH, SOD, and CAT levels, as well as iNOS levels in the hippocampus (81)

IGF-1 is the primary mediator of HGHs effects, responsible for most of the benefits associated with increased growth hormone levels
