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Description
Curr Opin Toxicol 14:17
In a healthy, unstressed cell, more than 90% of total glutathione exists in its active, "reduced" state, known as GSH
OCD = obsessivecompulsive disorder
K.OwenA.DanielS.JennerP.MarsdenC
In human hepatocellular carcinoma cell lines, both genetic or pharmacological disruption of DHCR7 and external administration of its metabolic substrate 7-dehydrocholesterol (7-DHC) effectively prevented the onset of ferroptosis (57)
3) Mechanical stress: excessive mechanical stress can induce ferroptosis in chondrocytes by disrupting iron homeostasis and increasing oxidative stress
