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The pro-inflammatory profile was determined by measuring interleukin-10, interferon- (IFN-), and nitric oxide levels

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217 Among these metabolic pathways, mitochondria, as the major organelles in iron utilization, involved in anabolic and catabolic pathways, play a crucial role in iron and energy metabolism

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Likewise, experimental study illustrated that expression of ePRL in the macrophages and monocytes are activated by adrenergic pathways with subsequent polarization of macrophages toward the inflammatory one (M1) [31]