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doi: 10.3390/ijms232415893

Abstract Systemic lupus erythematous (SLE) is a multisystem chronic autoimmune disease in which disrupted molecular pathways lead to multiple clinical manifestations

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From a pharmacokinetic perspective, all lignans demonstrate high gastrointestinal (GI) absorption, supporting their oral administration potential

Methods Experimental protocols Sixty C57BL/6J male mice (1820 g, 810 weeks, Changsheng Biotechnology Company, Liaoning, China) were housed and fed at the First Hospital of China Medical University, the Institute of Respiratory Disease, under quiet and controlled specific pathogen-free conditions

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