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This indicates a shift of tumor-associated macrophages towards an immune-stimulatory phenotype, which can enhance T cell activation

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In a similar randomized clinical trial with a smaller sample size, Abdelfattah et al., confirmed that adding L-carnitine to clomiphene citrate in the follicular phase and continuing administration into the luteal phase in clomiphene-resistant patients can improve ovulation quality and the rates of chemical and clinical pregnancy [18]

Participants were instructed to contact the study investigator immediately if they developed uncommon signs or symptoms or had any medical condition resulting in hospitalization or an emergency room visit

Regular monitoring of blood pressure and cardiac function is recommended during treatment