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Endothelium-dependent vascular effects of Pycnogenol

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As emphasized, the cytoprotective arguments are recovery of glaucomatous rats [11], normalized intraocular pressure [11], maintaining retinal integrity [11], recovering pupil function [11,12], recovering retinal ischemia [13], and corneal injuries [14,15,16,17]

Briefly, the ground rice leaf tissue (10 mg) from each treatment group was homogenized on ice in succinate assay buffer (100 L), and then centrifuged at 10,000 g for 5 min

Therefore, these mechanisms and therapeutic benefits require further validation in large-scale, controlled human trials

BPC-157 stands alone in its dual gut-brain action