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Additionally, the nose-to-brain pathway may enable the rapid delivery of mitochondria to the CNS within minutes

(Clinical Trial registration number: NCT05710068, date of first registration: 02/02/2023) A total of fifteen female volunteers with facial melasma were analyzed
3.5 High mobility group box 1 and inflammatory signaling HMGB1, a nuclear protein, functions as a transcription factor and a DAMP that amplifies inflammatory responses (45)

Int Rev Cell Mol Biol 340, 209344.Google ScholarPubMed Franceschi, C & Campisi, J (2014) Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

11 The result is bioenergetic failure

Importance of the Lipid Peroxidation Biomarkers and Methodological Aspects for Malondialdehyde Quantification
