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In intestinal Caco-2 cells, IL-1 decreases TER and increases inulin flux, which is in part mediated by the decreased expression and redistribution of occludin and increased expression of MLCK and MLC phosphorylation.46 It was also shown that the knockdown of nuclear factor-B p65 inhibits the decrease in occludin and increases in MLCK expression, indicating nuclear factor-B-dependent transcriptional regulation by IL-1.47 4

Multiple regression analysis of independent variables affecting acceleration time index in the study groups

Science 371 (6524), eabb0738

Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: dose-response, mechanisms, and clinical implications

Melatonin, as an endogenous hormone, has a wide range of actions

Tribulus terrestris L