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Many people feel some relief by midday, but as the day progresses, the muscles become fatigued from overcompensating, and the cycle of pain resumes

In patients on TPN, approximately 10 to 15 mmol of phosphorus (equivalent to 310 to 465 mg elemental phosphorus) per liter bottle of TPN solution is usually adequate to maintain normal serum phosphate, though larger amounts may be required in hypermetabolic states

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"My stock answer is that we just don't have enough data to support their use."