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9 Nucleic acid sequences and amino acid variable region sequences of the anti-EphA2 antibody 1F12 (SEQ ID Nos
The electrophilic modification of reactive cysteine residues on Keap1 is one of the most well-documented mechanisms: electrophilic phytochemicals like sulforaphane react with sensor cysteines (i.e., Cys151 and others) to inhibit ubiquitination of Nrf2 mediated by Keap1 and increase its half-life and nuclear localization [84, 90, 377]
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