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Glioblastoma stem cells (GSC) were treated with drugs immediately after seeding in six-well plates and cultured for 3 days

In contrast, another study has shown that higher doses of LA (100 mg/kg body weight) for different durations (7 and 14 days) can produce better effects in improving the fat contents in the liver, and even the effects of aging, which depresses the effect of LA on improving fatty liver, can be easily abolished by adding LA

This metabolic reprogramming not only supports cell proliferation but also elevates intracellular S-adenosylmethionine (SAM) levels, promoting epigenetic alterations and ultimately inducing the acquisition of NEPC characteristics (81, 82)

Nanomedicine 60 ShenD

Direct supplementation with glutathione may not be effective, as it is cannot enter small intestine cells intact

Finally, Garratt et al