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Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease Klaus Kannengiesser1, Christian Maaser, Jan Heidemann, Andreas Luegering, Matthias Ross, Thomas Brzoska, Markus Bohm, Thomas A Luger, Wolfram Domschke, Torsten Kucharzik ~ Review: Int J Mol Sci

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However, based on what we have learned from similar peptides, it could increase the risk of pancreatitis and gallbladder disease

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The addition of the N-terminal tyrosine residue was incorporated to facilitate radiolabelling for pharmacokinetic research studies, and has since become a standard part of the compounds structure as used in laboratory research