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This broad group encompasses biomarkers ranging from biochemical effect biomarkers measured in biological matrices such as 8-hydroxy-2-deoxy-guanosine (8-OHdG) in urine, or hormones in serum, to changes at macromolecular or structural levels, such as anogenital distance (AGD), structural changes by magnetic resonance images (MRI), or functional neural effects by behavioral tests

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4d, statistically significantly different from LD controls and vehicle-treated mice switched from WD to LD)

Another B-vitamin, vitamin B 2 , riboflavin, as a photosensitizing compound 359 , gives rise to the oxidative cleavage of folic acid and 5-methyl-THF by visible light, which is absorbed by and yields excited states of riboflavin 356,360,361

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Studies have shown that stroke may lead to decreased GSH synthesis through inhibition of glutathione peroxidase 4 (GPX4) [150,151,152]